Known as SARMs, these compounds have become popular in the bodybuilding community due to their ability to stimulate muscle growth, increase strength and enhance athletic performance. However, they’re a relatively new technology and we’ve only just begun to see the full potential of what these drugs can do. While they’re legal to sell and use, this does not mean that they have been vetted by the FDA, or even put through Gold Standard scientific trials. As such, it’s important to understand the risks involved with using them, especially long-term.
Unlike steroids, which have a much more scatter-gun effect, sarms are designed to specifically bind to androgen receptors in certain tissues like the muscle and liver. This allows them to have a more focused or targeted impact, which some believe will increase their effectiveness while decreasing the risk of side effects.
Because of their tissue selectivity, sarms can also be used to treat diseases such as osteoporosis, hypogonadism and prostate cancer. They’re also believed to promote the growth of fast-twitch muscle fibers, which are responsible for explosive movements and power.
SARMs are typically administered in liquid form, meaning they’re placed underneath the tongue (sublingual administration). This method of administration is preferred as it allows for easy entry into venous circulation, and avoids presystemic metabolism and potentially lower biological availability. Additionally, it reduces the chances of a negative taste or smell, which is sometimes the case with some sarms, such as MK-677.